Chrysalin (TP-508) for Sale

Disclaimer: All Iron Mountain Labz products are only intended for laboratory research use and are not approved for human consumption.

Overview of Chrysalin (TP-508)

Chrysalin (TP-508) is a synthetic 23-amino acid research peptide, also known as rusalatide acetate, derived from residues 508–530 of human prothrombin. This region represents the high-affinity receptor-binding domain of the native thrombin molecule. In laboratory research settings, TP-508 is investigated for how it interacts with a distinct subset of thrombin receptors expressed on fibroblasts, endothelial cells, and stem cells. These are interactions that occur independently of the proteolytic cleavage cascade associated with thrombin’s coagulation function. TP-508 is not a SARM, not a hormone analog, and not a dietary supplement. It is not approved by the FDA for human or veterinary use. Iron Mountain Labz supplies it for laboratory research purposes only and is not approved for human consumption.

Chemical Properties

Section	Details
CAS Number	121341-81-9
Molar Mass	2,312.44 g/mol
Chemical Formula	C₉₇H₁₄₆N₂₈O₃₆S
PubChem CID	91668177
IUPAC Name	H-Ala-Gly-Tyr-Lys-Pro-Asp-Glu-Gly-Lys-Arg-Gly-Asp-Ala-Cys-Glu-Gly-Asp-Ser-Gly-Gly-Pro-Phe-Val-OH
Peptide Length	23 amino acids
Sequence	Ala-Gly-Tyr-Lys-Pro-Asp-Glu-Gly-Lys-Arg-Gly-Asp-Ala-Cys-Glu-Gly-Asp-Ser-Gly-Gly-Pro-Phe-Val
Peptide Source	Residues 508–530 of human prothrombin
Synonyms	TP508, Chrysalin®, rusalatide acetate, TRAP-508
Ingredients / Composition	Chrysalin (TP-508), ≥98% purity (HPLC verified)
Physical Form	White to off-white lyophilized powder
Vial Format	lyophilized vial (flip-top aluminium crimp cap, sterile sealed)
Solubility	Soluble in sterile water or 0.1% acetic acid solution
Shelf Life	Up to 24 months when stored under recommended conditions in lyophilized form
Storage Instructions	Store at −20°C, protected from light and moisture. Avoid repeated freeze-thaw cycles. The vial seal should remain intact until use.
Classification	Research Use Only (RUO)

Chrysalin (TP-508) ‘ Mechanism of Action in Research Models

In preclinical cell culture systems, TP-508 has been investigated as a nonproteolytic agonist at a distinct subset of thrombin receptors. This is expressed on fibroblasts and endothelial cells, where it has been observed to stimulate endothelial nitric oxide synthase (eNOS) activation and rapid NO production. In preclinical animal wound healing models, TP-508 has been observed to stimulate endothelial cell chemokinesis and chemotaxis in a dose-dependent manner, with increased vascularisation markers noted at wound sites in TP-508-treated groups compared to saline controls. In isolated fibroblast cell systems, it has been investigated for its potential to modulate differential gene expression through a nonproteolytic receptor activation pathway, with preclinical data suggesting this may involve upstream signalling events distinct from those initiated by proteolytically active thrombin. Additionally, in vitro studies have examined its potential to affect stem cell proliferation signalling, with data from adipose tissue-derived stem cell cultures suggesting interaction with the PI3K/Akt pathway.

Why Buy Chrysalin (TP-508) from Iron Mountain Labz?

Researchers prefer Iron Mountain Labz to buy Chrysalin (TP-508) due to the following reasons.

• Purity of Chrysalin (TP-508) verified at ≥98% by HPLC per product specification
• Physical form confirmed as white to off-white lyophilized powder; passes visual inspection requirements
• Supplied as a sterile, sealed vial with a flip-top aluminium crimp cap
• Amino acid sequence AGYKPDEGKRGDACEGDSGGPFV confirmed against prothrombin residues 508–530 per specification
• The acetate salt form is supplied as standard for research applications

Note: The Peptide Single Vials category at Iron Mountain Labz also includes other thrombin-related and vascular biology research compounds. These peptides are studied for their effects on receptor signaling and angiogenesis pathways in preclinical research models.

For queries, complaints, or support, please contact help@ironmountainlabz.com

Risk & Handling

Chrysalin (TP-508) is a synthetic, nonproteolytic thrombin peptide. It is under investigation in preclinical research.

Risk Tier: MODERATE

This rating reflects TP-508’s bioactive receptor signaling activity at thrombin receptors, the bioactive concentrations used in preclinical research, and the need for proper handling to prevent accidental skin or inhalation exposure during reconstitution. Researchers must observe the following precautions at all times.

Handling Precautions: Chrysalin (TP-508) vials should be handled exclusively in a controlled laboratory environment by trained personnel. Use appropriate PPE at all times. Avoid direct skin and eye contact during reconstitution. Avoid inhalation.

Exposure Risks: No human safety data has been established for the research-grade formulation supplied here. Long-term or chronic toxicity data do not exist.

Storage: Store lyophilized TP-508 vials at −20°C in a dry, dark environment. Protect from light, heat, and moisture at all times. Avoid repeated freeze-thaw cycles. The vial seal should remain intact until use.

Frequently Asked Questions

Is Chrysalin (TP-508) legal in the United States?

Chrysalin (TP-508) does not hold an FDA-approved indication for any clinical use. It is available for laboratory and research purposes only in the United States. Researchers must comply with all applicable federal, state, and local regulations governing the purchase and use of research compounds.

What makes TP-508 nonproteolytic in research contexts?

TP-508 does not activate the proteolytic cleavage cascade associated with thrombin’s coagulation function otherwise. In preclinical settings, it interacts with a distinct receptor subset. This makes it a useful tool for isolating receptor-mediated signaling events in experimental models.

Is Chrysalin (TP-508) safe for human use?

No. Chrysalin (TP-508) is not approved by the FDA for human or veterinary use. Please review the Terms and Conditions before ordering.

What is the vial format for Chrysalin (TP-508) at IronMountainLabz?

Chrysalin (TP-508) is supplied as a lyophilized powder in a sterile, sealed vial with a flip-top aluminium crimp cap. This format maintains peptide integrity under recommended cold storage conditions. It is the standard for research-grade lyophilized peptides.

References

1. Olszewska-Pazdrak, B., Hart-Vantassell, A., & Carney, D. H. (2010). Thrombin peptide TP508 stimulates rapid nitric oxide production in human endothelial cells. Journal of Vascular Research, 47(3), 203–213. https://pubmed.ncbi.nlm.nih.gov/19893317/
2. Hembrough, T. A., Swartz, G. M., Papathanassiu, A., et al. (2001). Thrombin peptide, TP508, stimulates angiogenic responses in animal models of dermal wound healing, in chick chorioallantoic membranes, and in cultured human aortic and microvascular endothelial cells. Journal of Vascular Research. https://pubmed.ncbi.nlm.nih.gov/11888680/
3. Sower, L. E., Payne, D. A., Meyers, R., & Carney, D. H. (1999). Thrombin peptide, TP508, induces differential gene expression in fibroblasts through a nonproteolytic activation pathway. Experimental Cell Research, 247(2), 422–431. https://pubmed.ncbi.nlm.nih.gov/10066370/
4. Freyberg, S., Song, Y. H., Muehlberg, F., & Alt, E. (2009). Thrombin peptide (TP508) promotes adipose tissue-derived stem cell proliferation via PI3 kinase/Akt pathway. Journal of Vascular Research, 46(2), 98–102. https://pubmed.ncbi.nlm.nih.gov/18607113/