AC-Selank NH2

AC-Selank NH2

Disclaimer: All Iron Mountain Labz products are only intended for laboratory research use and are not approved for use outside of controlled research settings. All referenced research was conducted under IRB/IACUC/AWA-compliant protocols. This compound is not approved for human or veterinary use. 

Overview of AC-Selank NH2

AC-Selank NH2 (N-Acetyl Selank Amidate) is a synthetic heptapeptide and a structurally enhanced analog of Selank, itself derived from the endogenous immunomodulatory tetrapeptide tuftsin (Thr-Lys-Pro-Arg). 

The parent compound Selank incorporates a C-terminal Pro-Gly-Pro (PGP) extension to improve metabolic stability. 

AC-Selank NH2 further introduces N-terminal acetylation and C-terminal amidation, conferring enhanced resistance to enzymatic hydrolysis and extended receptor interaction profiles compared to the unmodified parent peptide.

AC-Selank NH2 is studied in preclinical research settings for its interaction with GABAergic neurotransmission pathways, serotonergic signaling networks, and immunomodulatory receptor systems. 

Investigational research has explored its role in neuroendocrine signaling regulation, neurotrophin expression, and inflammatory cascade modulation in controlled laboratory environments.

Section	Details
CAS Number	2212313-10-6
Molar Mass	793.9 g/mol
Chemical Formula	C₃₅H₅₉N₁₁O₁₀
Sequence	Ac-Thr-Lys-Pro-Arg-Pro-Gly-Pro-NH₂ (TKPRPGP)
IUPAC Name	(2S)-1-[2-[[(2S)-1-[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S,3R)-2-acetamido-3-hydroxybutanoyl]amino]-6-aminohexanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]acetyl]pyrrolidine-2-carboxamide
Synonyms	N-Acetyl Selank Amidate, AC-THR-LYS-PRO-ARG-PRO-GLY-PRO, N-Acetyl Selank
Ingredients / Composition	AC-Selank NH2 compound as key component with a purity of 98.8%
Shelf Life	2 years
Storage Instructions	Store as lyophilized powder at –18°C or below, protected from light and moisture
Disclaimer	AC-Selank NH2 is not approved for use outside of controlled laboratory research settings. It is legal for research purposes only.

Why Buy AC-Selank NH2 from Iron Mountain Labz?

Researchers prefer Iron Mountain Labz for buying AC-Selank NH2 due to the following reasons:

• At Iron Mountain Labz, AC-Selank NH2 is tested with HPLC and confirmed at 99.6% purity.
• The assay result of this product meets research-grade standards at 98.8%.
• A Certificate of Analysis (COA) is also provided for verification.

Frequently Asked Questions

Is AC-Selank NH2 legal in the United States? 

AC-Selank NH2 is a research chemical. It is not approved by the FDA for use outside of controlled laboratory settings in the United States. It can only be legally purchased for research purposes.

How does AC-Selank NH2 work in research models? 

AC-Selank NH2 is investigated for its interaction with GABAergic receptor systems, where preclinical data suggest modulation of inhibitory postsynaptic signaling cascades. Investigational findings associate the compound with serotonergic pathway regulation and tuftsin receptor engagement, influencing downstream immunomodulatory and neurotrophic signaling networks. The N-terminal acetylation and C-terminal amidation modifications confer enhanced resistance to aminopeptidase and carboxypeptidase enzymatic degradation, prolonging the compound’s investigational activity profile in preclinical settings.

What are the observed effects of AC-Selank NH2 in experimental settings?

Preclinical research associates AC-Selank NH2 with modulation of GABAergic inhibitory signaling, regulation of serotonergic receptor transmission, and attenuation of inflammatory cytokine cascade activity in controlled investigational settings. Research also suggests involvement in neurotrophin expression pathways and neuroendocrine feedback loop regulation in in vitro and in vivo preclinical models.

What are the noted adverse variables of AC-Selank NH2 in research settings? 

Comprehensive long-term data on AC-Selank NH2 remains limited, and further systematic investigation is required to fully characterize its adverse variable profile. Preclinical observations note potential variability in GABAergic receptor sensitivity under prolonged investigational exposure, possible modulation of serotonergic feedback dynamics, and concentration-dependent off-target receptor interactions at elevated research concentrations.

Where to buy AC-Selank NH2 online? 

AC-Selank NH2 is available for purchase at the Iron Mountain Labz online store. Each product is held to strict purity standards and comes with a Certificate of Analysis (COA) for complete research verification.